CuO-catalyzed conversion of arylacetic acids into aromatic nitriles with K4Fe(CN)6 as the nitrogen source

Fe(HSO4)3-Catalyzed Direct Conversion of Aldehydes into Nitriles Using Hydroxylamine Hydrochloride

Due to the importance and various applications of nitriles especially in medicinal productions, a new method for conversion of aldehydes to nitriles has been presented. Several nitrile-containing aromatic compounds were synthesized through the treatment of various aldehydes and hydroxylamine hydrochloride as nucleophile in the presence of ferric hydrogen sulfate as a heterogeneous, efficient, a...

CuO and Ag2O/CuO catalyzed oxidation of aldehydes to the corresponding carboxylic acids by molecular oxygen.

Furfural was oxidized to furoic acid by molecular oxygen under catalysis by 150 nm-sized Ag(2)O/CuO (92%) or simply CuO (86.6%). When 30 nm-size catalyst was used,the main product was a furfural Diels-Alder adduct. Detailed reaction conditions and regeneration of catalysts were investigated. Under optimal conditions, a series of aromatic and aliphatic aldehydes were oxidized to the correspondin...

Trimereation of Aromatic Nitriles

Ruthenium-catalyzed oxidative ortho-benzoxylation of acetanilides with aromatic acids.

Substituted acetanilides reacted with aromatic acids in the presence of [{RuCl2(p-cymene)}2], AgSbF6 and (NH4)2S2O8 in ClCH2CH2Cl at 100 °C for 24 h yielding ortho-benzoxylated acetanilides in good to excellent yields in a highly regioselective manner via C-H bond activation.

Conversion of aldoximes into nitriles and amides under mild conditions.

A series of Pd(en)X2 salts were used as catalysts for the conversion of aldoximes into nitriles and amides. Highlights of this protocol include the use of inexpensive polar solvents, including water, and moderate reaction temperatures. A high degree of selectivity in the reaction outcome was observed when using aliphatic vs. aromatic/conjugated aldoximes.